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Research studies have used doses between 600 mg and 1,800 mg daily, with 600 mg twice daily being commonly studied, but you should discuss appropriate dosing with your GP before starting supplementation
The risk of thyroid tumors in humans is currently not known, but tirzepatide it is contraindicated in patients with a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2
Do not rush the escalation, giving your gut time to adjust at each step greatly reduces IBS-disruptive side effects
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